Drug formulation is a process where various chemical substances are combined with the active drug to form a final medicinal product that is easy and safe for human consumption. It plays a pivotal role in the success of any pharmaceutical development program.
From the early stage preclinical studies to the late-stage clinical trials, formulation chemistry is used to design a safe and effective product. However, formulation chemistry is often overlooked during the early stages of drug develo
An excipient, also known as the pharmaceutical inactive ingredient, is a substance that is formulated along with the active drug substance during the manufacture of the medicinal product. It is intended to act as a carrier of the active drug substance and contribute to its stability, pharmaceutical profile, appearance, and patient acceptability.
In other words, it’s rare to find a drug containing only the active drug substance.
The various functions performed by the excipient in drug for
Topical formulations are becoming increasingly popular in the pharmaceutical industry. Not only have they allowed the delivery of the drug substance to a specific site, but they also avoid fluctuations in drug levels, inter and intra-patient variations, and improve the patient’s compliance with the treatment. In a topical formulation, the skin acts as a perfect medium for the delivery of the drugs having both local and systemic effects, but also acts a mechanical barrier for the penetration of
Ever wondered what makes up that tablet you gobble down during a headache?
It's not only the active drug but colourants, flavours, binders, and many other ingredients that make up the final product. Some increase the therapeutic properties of the drug, while others aid in the manufacturing process.
But, how to determine which products to combine and in what ratio?
That's where a formulation scientist comes in. The typical role of a formulation scientist comprise of:
Pharmaceutical formulation is the process of combining various chemical substances with the active drug to form a final medicinal product, which is called a drug mixture or drug formulation.
A drug formulation can be given to the patient in various forms like solid, semisolid or liquid. The type of the formulation given depends upon the patient's age, sex, and health condition and is specific for particular routes of administration.
Here we give a brief overview of the different forms of