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All Posts in Category: Preclinical Research

drug development process

5 Steps of Drug Development Process

It takes nearly 12 years for a new drug to reach the patient from a research lab. This time period is spent to discover and develop the drug to make it fit for human consumption. To know how the drugs are developed before you can buy them from the store; take a look at the steps of drug development process involved in preclinical studies: HANDPICKED RELATED CONTENT:  Are There Any Alternatives to Animal Testing in Preclinical Research? An Insight into Good Laboratory Practices for
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Why the Pig is a Good Preclinical Model over Rodents for Research on Wound Healing

Why the Pig is a Good Preclinical Model over Rodents for Research on Wound Healing?

All preclinical studies are designed to know the effectiveness of a particular treatment in human beings. With advancements in Science, in vitro studies have gained recognition to provide relevant information in research. But, animal testing continue to prove their utility in preclinical research studies. Rodents are used in maximum studies, but for wound healing research, pigs are considered fit as preclinical models. This is so because rodents differ from humans in a number of anatomical
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Preclinical research studies

Are There Any Alternatives to Animal Testing in Preclinical Research?

The number of animals used in preclinical studies is continuously increasing. Each year millions of experimental animals across the world are sacrificed in the name of scientific research. The pain, distress and death experienced by the animals during scientific experiments have been an issue of debate since long. Besides the major concern of ethics, there are few more disadvantages of using animals for scientific experiments, like requirement of skilled manpower, time consuming protocols, an
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Fourfold-Benefits-of-Conducting-a-Preclinical-Study

The Fourfold Benefits of Conducting Preclinical Study

Preclinical research studies form an important step in the process of drug development. It is the method of collecting adequate data that helps the researchers to decide whether it is safe for you to take a particular drug or not by conducting thorough studies on animals or plant specimens. But knowing the safety profile of the drug the only benefit or outcome of a preclinical studies? Absolutely not! A preclinical studies conducted to know the efficacy of a new drug or medical device a
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An Insight into Good Laboratory Practices for Preclinical Studies

An Insight into Good Laboratory Practices for Preclinical Studies

What is Good Laboratory Practice? Good Laboratory Practice (GLP) encompasses a set of principles for defining a framework within which laboratory or preclinical studies are planned, performed, monitored, recorded, reported, and stored for future reference. The need for GLP GLP was first instituted in the US when FDA (Food and Drug Administration) discovered numerous cases of wrong data submission and poor laboratory practices by toxicology labs and pharmaceutical companies across the United S
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How Preclinical Gene Models Push Advance Anti Diabetic Research?

How Preclinical Gene Models Push Advance Anti Diabetic Research?

Ants always eat sweet food but none of them haven't diabetes?- This could be the longing and despondent statement of any of the more than 300 million individuals worldwide affected by diabetes. Diabetes is debatably the most critical health care concern that has ignited a global crisis on the fiscal and physical status of all nations of the world. With its intricate association with obesity, hypertension, cardiovascular diseases, cancers, Kidney and Eye disease, Stroke, Alzheimer?s disease and
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Current Scenario and Impending Options in Colorectal Cancer Targets

  When I studied pharmacology my Professor defined chemotherapy as “thrashing up the patient with a cricket bat in the hope that you get the cancer on a winning streak”. Chemotherapy has plentiful of benefits, but the adverse effects can be noxious. We pharmacologists call “off-target toxicity” where the drug agents will kill the healthy cells as well as cancer cells. Whereas, the novel, targeted therapies are often designated as “silver bullets”. In my view, the targeted ther
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