We add spices to a meal for enhancing its taste and acceptance. Similarly, we have to add many additives in drug formulations to enhance their performance. These additives, also called excipients play a major role in the development of drug formulations. They hold together the components of the active drug substance and make it stable, palatable, and acceptable to the patients.
However, we often define the excipients as inert or inactive compounds which are added to the drug formulations. B
An excipient, also known as the pharmaceutical inactive ingredient, is a substance that is formulated along with the active drug substance during the manufacture of the medicinal product. It is intended to act as a carrier of the active drug substance and contribute to its stability, pharmaceutical profile, appearance, and patient acceptability.
In other words, it’s rare to find a drug containing only the active drug substance.
The various functions performed by the excipient in drug for
Topical formulations are becoming increasingly popular in the pharmaceutical industry. Not only have they allowed the delivery of the drug substance to a specific site, but they also avoid fluctuations in drug levels, inter and intra-patient variations, and improve the patient’s compliance with the treatment. In a topical formulation, the skin acts as a perfect medium for the delivery of the drugs having both local and systemic effects, but also acts a mechanical barrier for the penetration of
Ever wondered what makes up that tablet you gobble down during a headache?
It's not only the active drug but colourants, flavours, binders, and many other ingredients that make up the final product. Some increase the therapeutic properties of the drug, while others aid in the manufacturing process.
But, how to determine which products to combine and in what ratio?
That's where a formulation scientist comes in. The typical role of a formulation scientist comprise of: