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All Posts Tagged: drug development

Are Excipients used in Formulation Development Inert?

Are Excipients used in Formulation Development Inert?

We add spices to a meal for enhancing its taste and acceptance. Similarly, we have to add many additives in drug formulations to enhance their performance. These additives, also called excipients play a major role in the development of drug formulations. They hold together the components of the active drug substance and make it stable, palatable, and acceptable to the patients. However, we often define the excipients as inert or inactive compounds which are added to the drug formulations. B
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Challenges to Toxicity Testing

Challenges to Toxicity Testing in 21st Century

Toxicity testing of pharmaceutical drugs forms a critical part of the risk-benefit assessment that balances the beneficial effects of the drug against the observed toxic and adverse effects. Despite advances in toxicity assessment, many drugs and chemicals are marketed without adequate toxicology data. The increasing demand for nonclinical safety data in the early phase of drug development has posed the following challenges to toxicology testing, which must be adequately addressed: Deman
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Right Formulation for Topical Drug Development

How Important is the Right Formulation for Topical Drug Development?

Topical formulations are becoming increasingly popular in the pharmaceutical industry. Not only have they allowed the delivery of the drug substance to a specific site, but they also avoid fluctuations in drug levels, inter and intra-patient variations, and improve the patient’s compliance with the treatment. In a topical formulation, the skin acts as a perfect medium for the delivery of the drugs having both local and systemic effects, but also acts a mechanical barrier for the penetration of
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drug development process

5 Steps of Drug Development Process

It takes nearly 12 years for a new drug to reach the patient from a research lab. This time period is spent to discover and develop the drug to make it fit for human consumption. To know how the drugs are developed before you can buy them from the store; take a look at the steps of drug development process involved in preclinical studies: HANDPICKED RELATED CONTENT:  Are There Any Alternatives to Animal Testing in Preclinical Research? An Insight into Good Laboratory Practices for
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