Colorectal cancer, the cancer that originates in the colon or rectum, is the third most common cancer diagnosed in the United States. A plethora of studies have established a link between consumption of high-fat diet and increased risk of colorectal cancer, but the mechanism of this association was till now obscure. As reported in the journal, Stem Cell Reports, researchers from the Cleveland Clinic in Ohio have unfolded this mechanism. In a study that utilized mice as the models, researchers